Three-dimensional bioprinting adipose tissue and mammary Organoids feasible for artificial breast structure regeneration
نویسندگان
چکیده
منابع مشابه
Three-Dimensional Bioprinting for Regenerative Dentistry and Craniofacial Tissue Engineering.
Craniofacial tissues are organized with complex 3-dimensional (3D) architectures. Mimicking such 3D complexity and the multicellular interactions naturally occurring in craniofacial structures represents one of the greatest challenges in regenerative dentistry. Three-dimensional bioprinting of tissues and biological structures has been proposed as a promising alternative to address some of thes...
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Alginate hydrogel is a popular biologically inert material that is widely used in 3D bioprinting, especially in extrusion-based printing. However, the printed cells in this hydrogel could not degrade the surrounding alginate gel matrix, causing them to remain in a poorly proliferating and non-differentiating state. Here, we report a novel study of the 3D printing of human corneal epithelial cel...
متن کامل3-dimensional bioprinting for tissue engineering applications.
The 3-dimensional (3D) printing technologies, referred to as additive manufacturing (AM) or rapid prototyping (RP), have acquired reputation over the past few years for art, architectural modeling, lightweight machines, and tissue engineering applications. Among these applications, tissue engineering field using 3D printing has attracted the attention from many researchers. 3D bioprinting has a...
متن کاملReview Paper: Adipose Tissue, Adipocyte Differentiation, and Variety of Stem Cells in Tissue Engineering and Regeneration
Human adipose tissue represents an abundant, practical and appealing source of donor tissue for autologous cell replacement. Recent findings have shown that stem cells within the stromalvascular fraction of adipose tissue display a multilineage developmental potential. Adipose tissue-derived stem cells can be differentiated towards adipogenic, osteogenic, chondrogenic,myogenic and neurogenic li...
متن کاملConnexins act as tumor suppressors in three-dimensional mammary cell organoids by regulating differentiation and angiogenesis.
Connexins are tumor suppressors, and human breast connexin 26 (Cx26) and connexin 43 (Cx43) gap junctions are often down-regulated in breast cancer. We previously showed that Cx26 and Cx43 overexpressed in MDA-MB-231 breast cancer cells inhibited tumor growth in vivo but not in two-dimensional cultures. In the current study, we show that overexpression of Cx26 or Cx43 has tumor-suppressive prop...
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ژورنال
عنوان ژورنال: Materials & Design
سال: 2021
ISSN: 0264-1275
DOI: 10.1016/j.matdes.2021.109467